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Botox®  vs. Xeomin®: Choosing the Right Neurotoxin to Combat Wrinkles

By FoRM Health | January 29, 2025

At FoRM Health in Portland, Oregon, we specialize in helping you look and feel your best—which may include rewinding back the clock on wrinkles using neurotoxin injections. If you’re considering injections to smooth those unwanted signs of aging, you’ve likely come across two popular options: Botox® and Xeomin®. While both yield wonderful results, they have some key differences that may influence which one is right for you. Let’s break it down.

What Do Botox™ and Xeomin™ Have in Common?

Both Botox® and Xeomin® are FDA-approved neurotoxins (derived from botulinum toxin) for the treatment of wrinkles of the forehead, frown lines (also known as “11” lines), and crow’s feet around the eyes. They work by temporarily relaxing the muscles that cause the dynamic wrinkle (wrinkle caused by movement). The result? Smoother, more youthful-looking skin. Both treatments are quick, minimally invasive, and require no downtime.

3 Key Differences Between Botox® and Xeomin®

Purity of Formulation

    • Botox®: Botox contains additional accessory proteins alongside the active ingredient, botulinum toxin. While these proteins are generally considered innocuous, they theoretically could trigger an immune response resulting in antibody formation against the proteins, potentially reducing its effectiveness over time.
    • Xeomin®: Known as a “naked” neurotoxin, Xeomin® is free of added proteins, containing only the active ingredient. This pure formulation may reduce the risk of developing antibody resistance, making it a great choice for long-term use.

 

Stronger vs. Lighter Effect:

    • Botox®: With the additional proteins, Botox® has a greater molecular weight than Xeomin®, resulting in Botox™ having a more precise and “heavier” effect in the treated area. This feature makes it the better option for individuals with strong facial expressions or those seeking minimal to no facial movement within the treated area. 
    • Xeomin®: Without the accessory proteins, Xeomin™ has a more diffuse distribution within the treated area, resulting in a “lighter” land. This “lighter” effect is thought to create a more “natural” look, allowing for some muscle movement while turning down the wrinkle formation.

 

Onset + Duration of Results:

    • Botox®: With a slightly stronger effect, results are typically first noticed 3-5 days after treatment, though the full effect may take up to 2 weeks to settle in. On average, the results from one Botox® treatment lasts about 3 months.
    • Xeomin®: The lighter quality of Xeomin® may take a few more days to settle in, typically showing up 5-7 days after treatment, with the full expression of results showing up at 2 weeks, just like Botox®. Xeomin®, however, has been reported to last longer for some patients, averaging 3.5 month duration of results. The difference in duration of effect may be attributed to the accessory proteins.

Which One Is Right for You?

The best neurotoxin for you depends on your individual needs, lifestyle, and goals. Some patients prefer Xeomin® for its pure formulation and more natural aesthetic, while others stick with Botox® for its consistent and sometimes stronger results. During your consultation at FoRM Health, Dr. Kai will discuss your aesthetic goals and help you choose the option that’s best suited for you!

Why Choose FoRM Health for Your Neurotoxin Treatments?

At FoRM Health, we combine aesthetic expertise with a holistic approach to wellness. Our goal is not just to reduce wrinkles but to enhance your natural beauty and skin health. Whether you’re new to neurotoxin treatments or looking to switch things up, you can trust us to deliver personalized care with a natural aesthetic.

Ready to smooth away wrinkles and embrace a more youthful look? Schedule your consultation at FoRM Health in Portland today!

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We all have a goal of best metabolic health, right We all have a goal of best metabolic health, right?! Well it’s time to work smarter not harder 💪 🧠 🔥 

Sprinting + HIIT are powerful tools for metabolic health: 

⚡️ Improve insulin sensitivity (your cells use glucose more efficiently)
⚡️ Stimulate mitochondrial repair (better energy production)
⚡️ Preserve & build lean muscle, which supports a higher resting metabolism (your basal metabolic rate)
⚡️ Create an “afterburn” effect (increased calorie burn after the workout)

Our nutritionist also uses sprints + high intensity interval training for conditioning in tennis, backpacking, & dancing! 🪩 🎾 🪩 

If you’re just starting — this doesn’t mean going all-out on day one. Begin with short intervals, moderate effort, & plenty of recovery. 

We also don’t need & shouldn’t do HIIT everyday! 
2x per week is a sweet spot & you can get so much done in 10-20mins

& yes, longer forms of cardio like walking is super important for overall health too! Or long runs if you love to run but ROI for our metabolism really shines with HIIT. ⭐️ 

The goal isn’t maximum effort every day — it’s using intensity to our advantage! 

#hiit #metabolichealth #metabolism #feelbetter #feelstronger #sprint #movebetter #formhealthpdx
Reframe weight loss in 2026. The goal isn’t a smal Reframe weight loss in 2026.
The goal isn’t a smaller number on the scale — it’s more muscle.

Building and preserving lean muscle is the foundation of long-term strength, metabolic health, and resilience. The real win? Improving body composition: less body fat, more muscle.

Here’s where to focus 👇
• Strength train (prioritize lower body): 2–4x/week
• Move more overall: aim for ~8,000 steps/day
• Fuel muscle growth: eat about ~1.5 g protein/kg of goal body weight daily

If you’re doing the work and still not seeing results, targeted supplements and (when appropriate) medications can provide additional support.

Need a simple, delicious way to fuel an active day?
Check out Ellina’s Recipe of the Month: Pumpkin Pie Protein Smoothie 🎃💪
👉 Link in bio

#BuildMuscle #BodyComposition #MetabolicHealth #AgeWell #FoRMHealth #StrongNotSkinny #Longevity #MuscleMatters

#formhealth #formhealthpdx #functionalmedicine #naturopathicmedicine #integrativemedicine #naturopathicdoctor #feelbettermovebetterlookbetter #TopForm #sellwoodmoreland #ivtherapy #functionalnutrition #acupuncture #hormonehealth #hormonalharmony #feelbetter #musclematters
Here’s why Dr. Kai loves lower body strength-train Here’s why Dr. Kai loves lower body strength-training🤓

In women, muscle mass and strength begins a slow decline in our 30s, accelerates through menopause transition and—if ignored—can lead to frailty later in life. 

The importance of muscle mass + maintaining strength extends beyond our musculoskeletal system, as lean muscle mass also plays critical roles in immune function, cardiovascular health, and blood sugar regulation. Less muscle = poorer glucose control, higher risk for diabetes, cognitive decline + heart disease.

Fighting the good fight to fend off frailty is best to start early (think 30’s, early 40’s) when hormones are still working for you, though it’s really never too late to start. Building muscle helps protect us from falls, injuries, vulnerability + eventual loss of independence.

This is why lower body training is extremely important. Your glutes, quads, and hamstrings are your largest + most metabolically active muscle groups (+ they’re the first muscles to weaken in menopause) — they protect your joints, stabilize your spine, maintain your metabolism + keep you resilient + protected in your own body.

Dr. Kai’s go-to lower body exercises 🏋️‍♀️

🔥 Deadlifts
🔥 Squats
🔥 Hip bridges / hip thrusts

These compound movements recruit multiple muscle groups at once (abs, back, upper body), build strength for the real-world, and deliver the biggest return on investment.

Tips for success 👇
Lift moderate to heavy to build muscle
Aim for muscle fatigue with 8-10 reps, 2-3 sets/ exercise
Train lower body at least twice/week

Plan for the future - Lean into lower body training today!

#formhealth #formhealthpdx #movebetter #feelbetter #movebetterfeelbetter #functionalmedicine #hormonehealth #menopausehelp #muscleasmedicine #musclematters #bhrt #hormonetherapy #strongishealthy
Muscle matters — at every decade of life. 💪✨
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But as we age, it becomes non-negotiable.

Here’s why prioritizing muscle is one of the most powerful health decisions you can make:

🔹 Injury prevention + joint support
Strong muscles stabilize + protect joints, adds integrity to our physical framework, reduce injury risk + help with injury rehabilitation - muscle is key to resiliency + recovery!

🔹 Weight management + blood sugar control
Muscle is metabolically active tissue. Healthier muscle means better insulin function, steadier blood sugar, easier to manage weight, and meaningful protection against our most common chronic diseases — including heart disease, dementia, obesity, and diabetes. 

That’s why improving body composition matters more than chasing the scale: the real goal is building muscle while reducing visceral (abdominal) fat.

🔹 Preventing rapid muscle loss (sarcopenia)
During the menopause transition, declining hormones (mostly estrogen, testosterone and DHEA) accelerate muscle loss. Maintaining and building lean muscle helps preserve strength, bone density + keep us from fading away.

At FoRM, we don’t chase quick fixes — we build resilient bodies that age well. Strength training, nutrition, hormone support, and recovery all matter.

Muscle isn’t just about looking good. It’s about choosing to thrive rather than survive!

Over the next few weeks, we’ll be taking a deeper dive into the many benefits of muscle. Stay-tuned 🎧

#formhealth #formhealthpdx #movebetter #feelbetter #sellwoodmoreland #functionalmedicine #musclematters #regenerativemedicine #agedefy #hormonehealth
🎉 A joyful congratulations! We’re thrilled to sha 🎉 A joyful congratulations!

We’re thrilled to share that our Acupuncturist, Hilary Constant, welcomed her first baby, Wilder, in December. Hilary will be on maternity leave through March 2026, and we couldn’t be happier for her growing family.

Congratulations, Hilary + Chrissy!!

#babynews #babyannouncement #newadditions #formhealth #formhealthpdx #sellwoodmoreland #feelbetter #movebetter #lookbetter #portlandacupuncture
New year, fresh commitment. ✨ If 2026 is your yea New year, fresh commitment. ✨

If 2026 is your year to age intentionally, it starts with consistency. We’re re-sharing FoRM’s Slow Skin Aging Protocol—a results-driven approach to protecting, repairing, and strengthening your skin over time. No quick fixes - it’s about doing the right things, consistently.

SAVE THIS: The FoRM Protocol to Slow Skin Aging

Topicals that actually work
◽️ Vitamin C + antioxidants (AM)
◽️ Vitamin A/retinoids (PM)
◽️ Topical Estrogen* (a must for mid-life skin)

 Supplements with real data
◽️ Collagen peptides
◽️ Omega-3s (fish oil or cod liver oil)
◽️ Probiotics (gut-skin axis)

Why this combo works
✔️ Boosts collagen
✔️ Reduces inflamm-aging
✔️ Strengthens skin barrier
✔️ Restores firmness + hydration

Want more in-depth info? 
Visit our blog post - “Age slower. Look Better” using our link in bio.

Want to personalize this?
Schedule an Aesthetic consultation at FoRM Health in Sellwood.

#formhealth #formhealthpdx #TopForm #sellwoodmoreland #naturalaesthetics #healthyisbeautiful #agedefy #Skinrehab #glowup #SkinRejuvenation #PRFskinrejuvenation #naturalbeauty #microneedling #ipl #iplfacial #photorejuvenation #botox #biotherapeutic #advancedaesthetician #skinbetterscience #epionce #dermaplaning #microcurrent #hydrodermabrasion #nofilterneeded
Taking a moment to express gratitude for this incr Taking a moment to express gratitude for this incredible group of people that make FoRM Health what it is. 🤩 

We had the best time @thepeoplescourts being very merry & a little competitive! 😆 We love getting to play games, enjoy good food, steal presents from each other in our annual gift exchange, & have quality time together outside of the clinic. There’s a lot to be celebrated in what we get to do for our community and we are so fortunate to do it together! Happy Holidays ✨
✨ Stepping into 2026 with the goal to feel better, ✨ Stepping into 2026 with the goal to feel better, move better, and look better? Start now. ✨

At FoRM Health, we support your whole-body upgrade from every angle:

💛 Feel Better
Functional Medicine that optimizes hormones, balances nutrition, and boosts energy + longevity with IV Nutrient Therapy. This is your foundation for a stronger, healthier year ahead.

💪 Move Better
Say goodbye to pain holding you back. Our physical medicine, sports rehab, and regenerative orthopedic therapies (PRP, MFAT + more) target the root cause — so you stay active, capable, and confident in 2026.

✨ Look Better
Our Look Better Memberships give you a strategic, customized skincare plan that actually works. One flat monthly rate. Real results. A simpler path to glowing, youthful skin.

Ready to start your transformation? Learn more in our bio link!

1️⃣ Explore our membership tiers
2️⃣ Book your free aesthetic consult
3️⃣ Lock in your monthly treatments + get ready to thrive

Let’s make 2026 your strongest, healthiest, most radiant year yet.

#FeelBetter #MoveBetter #LookBetter #FoRMHealth #AestheticMedicine #FunctionalMedicine #RegenerativeMedicine #PRP #MFAT #HormoneHealth #Longevity #2026Goals
We’d all like a little less stress, right? 🧖‍♀️ O We’d all like a little less stress, right? 🧖‍♀️ 
Our team constantly touts the importance of stress management & this is how the FoRM fam practice what they preach! What’s your favorite way to stress less? Hopefully a treatment at FoRM is one of them 😉 

#formhealth #stressless #stressmanagement #feelbetter #takecareofyourself #joyismedicine #sellwoodmoreland #functionalmedicine #healthiswealth
Stress is inevitable. Movement makes it more manag Stress is inevitable. Movement makes it more manageable ⚡

Movement isn’t just about aesthetics or weight loss — it’s powerful medicine for your brain and nervous system. Regular movement resets stress hormones, improves sleep, elevates mood (hello endorphins), and builds true resilience from the inside out.

Here’s how our FoRM providers personally use exercise to offset life’s stressors👇

• HIIT classes with colleagues 🏋️‍♀️
• Train for a new challenge (ie triathlon) 🏊‍♀️🚴‍♂️🏃‍♀️
• Butt-busting stair climbs 🔥
• Long hikes in nature 🌲
• Walking the dogs (daily therapy) 🐕
• Run clubs with friends 👟
• Golf in beautiful surroundings ⛳

Whether it’s a casual walk or a new challenge — just move. Consistency beats perfection, every time.

#StressLess #MoveBetter #ExerciseIsMedicine #NervousSystemReset #FoRMHealth #MentalHealthMatters #Endorphins #OutdoorTherapy #WellnessLifestyle #ChallengeYourself #formhealth #sellwoodmoreland
SAVE THIS: The FoRM Protocol to Slow Skin Aging T SAVE THIS: The FoRM Protocol to Slow Skin Aging

Topicals that actually work
◽️ Vitamin C + antioxidants (AM)
◽️ Vitamin A/retinoids (PM)
◽️ Topical Estrogen* (a must for mid-life skin)

 Supplements with real data
◽️ Collagen peptides
◽️ Omega-3s (fish oil or cod liver oil)
◽️ Probiotics (gut-skin axis)

Why this combo works
✔️ Boosts collagen
✔️ Reduces inflamm-aging
✔️ Strengthens skin barrier
✔️ Restores firmness + hydration

Want to personalize this?
Schedule an Aesthetic consultation at FoRM Health in Sellwood.
Rx only - work with an experienced provider

#formhealth #formhealthpdx #TopForm #sellwoodmoreland #naturalaesthetics #healthyisbeautiful #agedefy #Skinrehab #glowup #SkinRejuvenation #PRFskinrejuvenation #naturalbeauty #microneedling #ipl #iplfacial #photorejuvenation #botox #biotherapeutic #advancedaesthetician #skinbetterscience #epionce #dermaplaning #microcurrent #hydrodermabrasion #nofilterneeded
✨ FoRM Holiday Pop-Up Event ✨ Get in the spirit w ✨ FoRM Holiday Pop-Up Event ✨

Get in the spirit with our one-day beauty event — the perfect excuse for a holiday glow-up before the festivities kick in.

📅 Saturday, Dec 6th
⏰ 10am–3pm
📍 FoRM Health

Treat yourself to a glow-up before the holidays with your choice of:

💦 Holiday HydraLift Facial — $125 (40 minutes)
Features: Lite-peel, ultrasonic exfoliation + microcurrent lift for instant glow.

💉 Botox or Xeomin — $12/unit
Smooth, refresh, and look photo-ready for every event.

You can book one or both treatments — totally up to you.

👉 Spots are limited. 
Email dr.herman@formhealthpdx.com to reserve your appointment.

#holidayglow #formhealth #hydrafacial #botoxportland #xeomin #skinglowup #pdxevents #aestheticmedicine #lookbetterfeelbetter #glowup

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